Take Supplements to Work on the Dermis

You need to take supplements to work on the dermis, as topical treatments cuts the damage only the epidermis. Skin is 20% epidermis, the barrier that protects us from the environment, and 80% Dermis, which acts as foundation for epidermis.

A mixture of grape-seed extract, coenzyme Q10, and Vitamin С and A can reverse skin changes in both photo aging and chronological aging.
Vitamin A it's an antioxidant and can be used to treat acne, aging skin and hyper pigmentation.

A vitamin A, or retinol, is one of the most powerful treatment to several clinical condition For the skin. Each of the forms of vitamin A –Retinol, Retinyl Acetate and Retinyl Palmitate-has specific reasons why it would selected for a specific issue.

Guidelines for Treating Acne
This is a working classification for addressing acne that follows the American Academy of Dermatology recommendations.

Mild acne—only comedones.
Use a salicylic acid 2-5% cleanser twice daily and follow in the evening with retinol or retinyl acetate, 0.5%, at night. Reduce fatty and sugar-laden foods, and make sure green and yellow vegetables are consumed.

Lesions should clear in 3-6 weeks. Follow up with bi-monthly visits for at least six months, then, at six-month intervals.

Mild acne with comedones, macules and papules.
Follow the same regimen as mild acne with only comedones, but add 2.5-5% benzoyl peroxide. At this stage, infection has started and the Propionibacterium acnes needs to be stopped from making a pustule.

Follow weekly with oxygen treatments—a proven topical oxygen or a water-based aerosol of oxygen is ideal. Dry oxygen is not as effective.

Getting into the follicle with molecular oxygen is the goal because P. acnes is anaerobic and does not like oxygen. You should see this client every week until the lesions are clear.

Papules and pustules.
Pustular acne means that the infection has gotten worse. Physicians generally use oral antibiotics at this stage, but you could use all of the aforementioned agents plus 5% niacinamide cream, which is available from some suppliers.

Niacinamide at 5% has been shown to be as effective as clindomycin when applied topically.15 If you are not getting a response in a week, the client should be referred to a physician.